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OCR: creting In sixteen patients with large prolactin-s es. The tumours, thirteen showed similar chan ere not three patients in whom these changes w observed consisted of: associated . A patient with a pituitary cyst that wa the with a small prolactinoma, but in whor st. majority of the pituitary mass was the c our that . A patient with an extremely large tum ge. (The was reduced in size but still remained la nety per patient's senum prolactin level fell by n ml therapy). cent but still remained elevated at 328ny (6560mu/1) at the end of nine months o r six weeks . A patient who had only been treated f ocal and in whom there was as yet only equi amor evidence of reduction in the size of the